壳聚糖基抗菌水凝胶在生物医药与食品保鲜领域的研究进展

王志超; 夏福建; 姜玉

doi:10.19554/j.cnki.1001-3563.2026.11.010

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包装工程（技术栏目） ›› 2026, Vol. 47 ›› Issue (11) : 94-102. DOI: 10.19554/j.cnki.1001-3563.2026.11.010

先进材料

壳聚糖基抗菌水凝胶在生物医药与食品保鲜领域的研究进展

王志超¹, 夏福建¹, 姜玉^1,2*

作者信息 +

Research Progress of Chitosan-based Antibacterial Hydrogels in Biomedicine and Food Preservation

WANG Zhichao¹, XIA Fujian¹, JIANG Yu^1,2*

Author information +

文章历史 +

摘要

目的探究壳聚糖基抗菌水凝胶的研究现状、性能改进策略及应用前景,推动其在生物医药和食品保鲜等领域的发展。方法系统梳理近年国内外相关文献,从壳聚糖基抗菌水凝胶的性能改性策略及在生物医药与食品保鲜领域的应用进行综述分析。结论壳聚糖因其优异的生物相容性、可降解性及广谱抗菌活性,在生物医药、食品工业等领域展现出巨大潜力;但单一壳聚糖存在水溶性欠佳、力学性能弱以及抗菌性不足等缺陷,这些问题极大限制了其实际应用。将壳聚糖构建成水凝胶体系,可借助其三维网络结构,有效改善上述短板,提升材料的使用性能;同时,通过化学改性、纳米粒子复合、植物精油复合等改性方式,可进一步优化壳聚糖抗菌水凝胶的综合性能,拓宽其应用场景,目前其应用研究主要集中于伤口修复、药物缓释、食品保鲜等领域。可为后续高性能壳聚糖基抗菌水凝胶的研发与应用提供些许参考。

Abstract

The work aims to explore the current research status, performance improvement strategies and application prospects of chitosan-based antibacterial hydrogels, and to promote their development in biomedicine and food preservation. This paper systematically reviewed the relevant domestic and foreign literature in recent years, and conducted a comprehensive analysis on the modification strategies of the performance of chitosan-based antibacterial hydrogels and their applications biomedicine and food preservation. Chitosan, owing to its excellent biocompatibility, biodegradability, and broad-spectrum antimicrobial activity, has demonstrated significant application potential in fields such as biomedicine and the food industry. However, native chitosan suffers from inherent drawbacks such as poor water solubility, weak mechanical strength, and instability of its antimicrobial properties under varying environmental conditions, which limit its practical applications. The three-dimensional network structure of hydrogels can effectively compensate for these shortcomings. Meanwhile, through various modification methods such as chemical modification, nanoparticle composites, and plant essential oil composites, the comprehensive performance of chitosan antibacterial hydrogels can be further improved, thereby expanding their application scope. At present, its application research mainly focuses on wound repair, drug sustained-release, and food preservation fields. It can provide some references for the subsequent research and application of high-performance chitosan-based antibacterial hydrogels.

导出引用

王志超, 夏福建, 姜玉. 壳聚糖基抗菌水凝胶在生物医药与食品保鲜领域的研究进展[J]. 包装工程. 2026, 47(11): 94-102 https://doi.org/10.19554/j.cnki.1001-3563.2026.11.010

WANG Zhichao, XIA Fujian, JIANG Yu. Research Progress of Chitosan-based Antibacterial Hydrogels in Biomedicine and Food Preservation[J]. Packaging Engineering. 2026, 47(11): 94-102 https://doi.org/10.19554/j.cnki.1001-3563.2026.11.010

中图分类号： TB34

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