The work aims to investigate the design patterns and technical approaches of anti-sympathetic packaging for the purpose of preventing sympathetic detonation between ammunitions. The execution principles of anti-sympathetic detonation packaging technology of ammunition and the application cases of typical anti-sympathetic packaging were analyzed and summarized, by comprehensively applying the technical methods regarding safety assessment of ammunition, sympathetic detonation, sympathetic detonation test, blast protection and packaging design. The four technical methods including explosion isolation, denotation resistance, explosion venting and shock absorption, were the main basis used to design anti-sympathetic detonation packaging of ammunition. The anti-sympathetic detonation packaging of ammunition is one reliable approach to solve the sympathetic detonation. For the specific implementation of the anti-sympathetic detonation packaging of ammunition, the safety requirements and sympathetic detonation test results of ammunition, the economy of protective packaging and other factors should be considered.