The work aims to reduce and eliminate the wasted transport packaging materials in E-commerce mode, and standardize the express transport carrier. A modular, standardized and easily disassembled turnover box combined with the plastic corrugated board was designed and applied in the enterprise, between enterprises and E-commerce companies, and in the E-commerce distribution logistics. ANSYS simulation analysis showed that, the designed turnover box had a compressive carrying capacity of 10 kN, approximately two times that of the 0201 AB five-layer corrugated box with the same size. The inner frame combination makes the edge compressive strength of the designed turnover box excellent. The splicing structure greatly increases the life of the turnover box. The plastic corrugation can adapt to a variety of buffer requirements, so that the use of transport packaging materials can be reduced to a certain extent.