The work aims to research the loading problem of packaging unit of vehicle tactical reserve equipment, and provide technical and method basis for improving the loading capacity of packaging unit of vehicle tactical reserve equipment of the army. The main constraints such as space, quality, loading balance and placement stability of the loading optimization model and the handling methods of constraints were analyzed. The heuristic algorithm was used to design the model solving process reasonably, and a hybrid genetic algorithm combined with heuristic algorithm and genetic algorithm was proposed. Taking the pallet loading as an example, the specific loading process was illustrated. The example results showed that, the pallet space utilization rate was more than 98.3%, and the loading unit containers had high stability. The algorithm can reduce the number of loading containers, improve the container loading capacity, and optimize the loading of the equipment packaging unit, which is of great significance to improve the rapid support ability of vehicle tactical reserve equipment.