The work aims to study the effect of density, hole distribution and load strain rate on the deformation and energy absorption of the aluminum foam. The compression experiment study was conducted on the aluminum foam with three different ranges of density under various strain rates. The experiment results showed that, under the loading rate of 10 mm/min, the average yield stresses of the foam with the density ranges of 0.27~0.33 g/cm3 and 0.47~0.53 g/cm3 were 1.3 and 7.2 MPa, respectively. The average strain energy densities of these two foams were 0.8 MJ/m3 and 3.8 MJ/m3, respectively. Furthermore, the strain energy density of the foam (0.453 g/m3) with a nonuniform distribution of the hole was 3.26 MJ/m3, while the strain energy density of the foam (0.449 g/m3) with a uniform distribution of the hole was 3.84 MJ/m3. With the increasing density, the yield stress and the stress of the foam corresponding to various strains are increased. The energy absorption ability of the foam with the uniformly distributed holes is much better than the foam with the nouniformly distributed holes. Moreover, the loading rate has certain effect on the stress-strain behavior of the foam, but it has no effect on the energy absorption ability of the foam.