The work aims to study the content and migration of nonylphenol and octylphenol in food contact materials and analyze the risk of food exposure. The method used to determine the nonylphenol and octylphenol content and migration by liquid chromatography-mass spectrometry was established, and the related test data were analyzed statistically. Under optimized condition, the nonylphenol and octylphenol were in good linear relation within the range of 5~200 μg/L. The correlation coefficients were greater than 0.999. The lower limits of quantitative for the content and migration detected were 0.1 mg/kg and 10 μg/kg, respectively. The average recoveries of standard addition at three spiked levels of 10, 100 and 200 μg/L were 85.6%~89.2% and 94.3%~100.6% for content and migration determination, respectively. The relative standard deviation for both content and migration determination was less than 15%. 30 batches of plastic wrap and composite packaging bag samples were tested. The results were as follows: 6 batches of samples were detected containing nonylphenol or octylphenol, accounting for 20% of the total samples. In these 6 batches of samples, the result of nonylphenol migration in 1 batch of samples was positive, accounting for 16.7%. The nonylphenol and octylphenol may be contained in plastic wrap and composite packaging bags, and were easy to migrate to food stimulants. The migration increases as the temperature rise and time extension. There is a certain risk of nonylphenol and octylphenol in plastic wrap and composite packaging bags, which should be taken seriously.