The work aims to study the effect of oxidized starch adhesive of preservative paper coating on NaClO2 retention rate and ClO2 release rule of the paper. Through the SEM image of the surface and cross section of the preservative paper, its structure characteristics were determined. Oxidized starch adhesive was coated on the paper base surface, and the NaClO2 retention rate and ClO2 release of preservative paper were calculated by the method of iodimetry. The oxidized starch adhesive coating formed on the surface of the paper could effectively reduce the influence of the paper base structure on the NaClO2 retention rate and ClO2 release. NaClO2 retention rate and ClO2 release increased, and the total release of ClO2 was 3.4786 mg, which was 70.82% higher than before. The oxidized starch adhesive coating has improved the NaClO2 retention rate and ClO2 release.