These contemporary enterprises are facing the complex and changing service experience and organization structure of design issues that compared with the traditional design tasks just involved function and shape. The solutions of these problems depend on the integration of nature science and social science. We can find the solution to the problems through the design thinking, which is human-centered, based on specific circumstances, to integrate interdisciplinary knowledge for treating the complex problems. Design thinking must not only separately consider design innovation, but also observe and think about the innovation of the whole system.