The work aims to more conveniently transport and package red wine and other fragile glassware and provide them with some functions like transport safety, beauty and integration of sales and exhibition. Taking 750ml sloping-shoulder red wine bottle as an example, the modeling of lining structure was designed by selecting type A and type B corrugated boards based on its stiffness and folding performance, thus achieving the lining structure by folding one-piece corrugated board. In addition, maximum acceleration curve of red wine bottle was obtained based on dropping test of transport packages of red wine; then solid model was established by using Pro/E software and imported into the finite element software ABAQUS for drop simulation; finally, the response acceleration curve of packages was obtained. The maximum acceleration in the Z direction was 215.33 m/s2, much lower than the impact acceleration in the horizontal direction, namely, its cushioning performance of drop impact was better than that in the horizontal direction. Moreover, compared with the results of drop test, the errors within the acceptable limits indicated that the finite element model built was reasonable and this model could better reflect the dynamic cushioning property of the red wine packages in the process of dropping. Such lining structure is entirely made of environmentally friendly corrugated boards easy to be processed and formed. And the breakage rate of red wine in the transport process is reduced because of the good cushioning properties and packaging characteristics of corrugated boards. Due to the design of lining structure with all corrugated boards, the defects of the traditional transport package of the red wine are overcome, and the deficiency of single structure of the paper package for red wine is also made up. Moreover, the analysis on the maximum response acceleration shows that such structural design can meet the requirements of impact protection when a red wine bottle is placed upright.