The work aims to research a new process of aluminum-plastic film printing and packaging to improve the production efficiency of lithium battery packaging. The process of aluminum-plastic film packaging, which was coated firstly, then printed and encapsulated, was used to replace the traditional process of packaging lithium battery with aluminum plastic. The chemical resistance, abrasion resistance, adhesion, gloss and other indicators of aluminum-plastic printing film were tested under the new process. The new technology can not only broaden the printing type and improve the production efficiency, but also can achieve high-precision printing operations and improve the printing quality of aluminum-plastic film. Tests showed that, under the new process, the chemical resistance and abrasion resistance of aluminum-plastic printing film were excellent, the adhesion could be up to 100% and the average gloss was 8.4. Compared with the traditional technology, the new technology has a strong advanced nature, which can be applied to aluminum-plastic film packaging and packaging operations of lithium battery for mobile phones.