The work aims to study simulations and experiments to verify that the temperature distribution under the actual working conditions meets the requirements of sealing. Modeling of the heat sealing mechanism of food carton packaging machine was done with the Comsol software, and the electromagnetic field and temperature field of the model were calculated, simulated and analyzed, so as to simulate the magnetic flux distribution in the electromagnetic field and the temperature distribution in the temperature field, and to figure out their relationship through analysis. Moreover, the high-frequency heat sealing test for food carton packaging machine was verified. At the same heat sealing time, the greater the current value, the higher the heat sealing temperature and the wider the heat sealing width. At the same current value, the longer the heat sealing time, the higher the heat sealing temperature and the wider the heat sealing width; but the effect was not as significant as for the change in the current value. When the working conditions were: I=5.5 A, t=0.3 s, it could meet the requirements of good sealing. The sealing temperature is symmetrical in the sealing area. Compared to the change in the heat sealing time, the change in the current value among the parameters has a greater impact on the heat sealing temperature.