The work aims to solve the problem that the parameters for processing the micro-pores of different sizes cannot be quickly and accurately determined in the actual production of processing microporous films by CO2 laser and to guide the application of microporous film packaging materials in the engineering. When the laser was 6~30 W and the drilling time was 0.4~4 ms, PP packaging films that were 0.04, 0.06 and 0.07 mm thick and PE packaging films that were 0.035, 0.05 and 0.07 mm thick were processed. The diameter and length of the micro-pores were measured and the test data were analyzed. The micro-pores with diameter of 50~400 μm on the PP/PE films whose thicknesses were 0.035~0.07 mm and the micro-pores with diameter of 53~257 μm and pore length of 100~161 μm on the PP films that were 0.06 mm thick were processed. As for the microporous films processed by laser, the pore diameter is increased with the increase in the drilling time. Micro-pores of different diameters can be obtained by adjusting laser power and drilling time. The laser energy required to process PE films is significantly greater than that required by PP films. The thicker the film, the higher the laser energy required by drilling. The length of micro-pore is increased relative to the film thickness. Moreover, the larger the micro-pore diameter is, the longer the pore is.