The work aims to propose the method to evaluate perceptual sharpness combined with complex wavelet domain and total spatial variation with respect to the problem that the definition evaluation method combined with frequency domain and spatial domain is time-consuming and not highly consistent with the subjective evaluation and so on. The resolution charts of original image and reference image were calculated on the complex wavelet domain through local phase consistency. The resolution charts of original image and reference image were calculated on the spatial domain through total spatial variation. The weighted geometric average of the respective two resolution charts of original image and reference image was carried out to obtain two overall perceptual sharpness charts. The similarity of two perceptual sharpness charts was calculated to obtain the perceptual sharpness of the original image. The results showed that the SROCC value on LIVE database reached 0.9476, CC value reached 0.9483 and the test image consumed 6.003 s. Experimental results show that the evaluation performance of the algorithm herein is better than that of the evaluation method similarly combined with frequency domain and spatial domain and it can reduce the computational complexity, consume less time and better conform to the subjective perceptual sharpness of human vision.