The work aims to predict and analyze the cushioning performance of EPE cushion material under repeated dropping shocks. Stress-energy method was used to obtain and analyze the cushioning curves under repeated dropping shocks. Then, the change in cushioning performance of EPE cushion material was evaluated. After the EPE samples were subject to multiple dropping shocks, the thickness decreased and the cushioning performance reduced. In the process of designing the cushion packages, the environmental factors should be taken into full consideration. To sufficiently protect the products, the cushion thickness should be added properly according to the conditions of logistics environment.