The work aims to provide a diversified and automated carton packaging machine in E-commerce express industry, so as to reduce the labor intensity of employees and improve the efficiency of carton packaging. The carton packaging machine was mainly composed of base support device, adjustment device for cardboard box, finger packaging device with controllable linkage mechanism, carton rotating device, adhesive tape packaging device and control system. Dual screw sliding table was designed to achieve the alignment and centering of cartons of different specifications and dimensions. The flap folding and packaging of cartons of different specifications and dimensions was realized by controlling the motion parameters of driving links of controllable finger packaging device. Adhesive tape packaging device was composed of direct-acting electromagnet, mini vacuum pump, adhesive disc and other parts. Cross packaging of carton and automatic cutting of adhesive tape were carried out with the coordination of adhesive tape packaging device and carton rotating device. Effective working space of the prototype machine was 550 mm×450 mm×300 mm. The prototype machine could package the cartons ranging from 140 mm×140 mm×180 mm to 550 mm×450 mm×300 mm. Each carton packaging time was about 60 s. The carton packaging machine can finish the packaging of cartons of different types and the cross packaging of adhesive tape, which achieves the diversification and automation of packaging. Characterized by small space occupation, flexible and controllable functions and low cost, the packaging machine can improve the working efficiency of E-commerce express employees.