The work aims to test the dynamic strain of printing blanket at the impression contact region by the infrared thermal imaging system. The geometric model of the impression contact region was built. Combined with thermos-elastic effect and thermal radiation theory, the function relationship between temperature and strain was analyzed. The temperature distribution of blanket at the impression contact region was obtained with the infrared thermal imaging system. Finally, through the finite element simulation, the strain cloud at the blanket impression region was obtained. Along the axial direction, the blanket temperature and strain at the impression contact region were unevenly distributed. The temperature at axis end was higher than that in the middle region. The strain at axis end was intensive. If the nodal displacement was large, the deformation would be large; for the middle region, such case would be just the opposite. The dependant variables of the middle region were lower than those at axis end. The infrared thermal imaging technology used to test the blanket dynamic strain in the printing process is feasible.