The work aims to analyze and summarize the initial factors in designing the widely applied continuous rotary machine with multi-functions of bottle cleaning, sterilizing, filling and sealing. By analyzing the basic technological process, the conditions, parameters and restrictions of using the continuous rotary machine with multi-functions of bottle cleaning, sterilizing, filling and sealing were pointed out. The dependence of filling workstation number, rotational speed and productivity were also specified. The moving path of bottle was designed. The bottle clamping structure for the first and last turntable layers was analyzed and its features were pointed out. The upgraded conveying and transferring mechanism was able to reduce the frequency of bottle rolling over by 1~2 times. The duration of cleaning and sterilizing processes was extended to 1.2 ~ 1.5 times than before, which helped in improving product quality. In conclusion, the newly developed continuous rotary filling machine is able to grip bottle stably and smoothly, which provides a reference for serialized design and technology updating.