The work aims to develop high-strength mould-proof corrugated carton for bedding and clothing. A six-layer corrugated carton was made by composite technology. Liner paper and surface paper combined the mould-proof and moisture-proof functions on the carton by coating. The strength, waterproof and mould-proof performances were tested. Edge crush strength and puncture strength of composite board were 21 060 N/m and 39.4 J respectively, which were 1.62 and 2.19 times of German Standard. Water absorption decreased from 34.7 g/m2 to 2.56 g/m2 after water-proof coating. No mould was found on the anti-mould coating board after 7 days anti-mould test in the 28 ℃ and RH 90% environment. No mould was found on the inner and outer surfaces of the carton and also the inside contents. The box anti-mould ability reached toⅠgrade through 28 days test. In conclusion, mould-proof carton with big strength and good mould-proof and mositure-proof functions can protect bedding and clothing from mould.