It introduces the research progress of isotactic polypropylene (iPP) modification with nucleating agent and aims to improve the transparency and impact strength of materials. Modification methods and mechanism were discussed in details from transparency modification, toughening modification, synergistic modification of the two. And the current research progress was pointed out. In terms of transparency modification, α-nucleating agent was added to improve the transparency of iPP. The temperature and light transmittance were researched in depth. In the toughening modification aspect, β-nucleating agent was adopted to improve the impact properties of iPP and its impact strength was studied. To improve the transparency and impact properties of iPP, synergistic modification of α/β nucleating agents could be used. In conclusion, the compound of α/β nucleating agents will increase the transparency of iPP to 80%~90%, and improve its impact strength to some degree.