In order to more precisely control the temperature of heating-sealing device and improve the quality of pocket lamination, a design scheme for temperature controller was put forward based on fuzzy self-tuning PID. This design combined the traditional PID control mode and the fuzzy control and adjusted PID parameters online. It applied the traditional PID and the fuzzy PID control algorithms to the programming of Siemens PLC. Compared with the traditional mode, the fuzzy PID control method was more stable in controlling the heating temperature and effectively improved the response speed and the control accuracy. Fuzzy PID temperature control system has better effect on temperature control and can improve the sealing quality of heat-sealing device.