In order to reduce the vibration of the sealing mechanism of aluminum foil cartooning machine during the working process and solve the problem of cam return spring fracture, the dynamic characteristic of the sealing mechanism was analyzed by using Adams. The influence of the cam profile and the return spring stiffness was also analyzed. Besides, the effect of cartooning speed was also taken into account. As the simulation result showed that the vibration often appeared before the end of sealing process when the remaining stage was about to start. Increasing the return spring stiffness was helpful for mitigating the vibration, but the effect was not obvious when the return spring stiffness continued to increase. The impact phenomenon was not obvious and the sealing mechanism had a good performance when the return spring stiffness was 0.4 N/mm and the cartooning speed was 2 pcs/s.