This work aimed to study the effect of paper structure, anti-oil agent and its adding method on the oil resistance of packaging paper. Through analyzing the composition and structure of paper, the effect of paper structure on oil-proof performance was discussed, as well as the method to improve the oil-proof performance of paper from the point of paper structure. Through analysis of the types, structures and bonding methods with paper of oil-proof agents, the characteristics and application trend of oil-proof agents were discussed. The food safety, environmental friendliness and cost controlling of oil proof agents were emphasized and the development trend of oil proof agents was analyzed. Through analysis of adding method of oil proof agent into paper, the effect of adding methods on the oil-proof performance and cost of paper was discussed. Improving the paper pulp could not only increase the oil-proof performance of paper, but also reduce the production cost of paper. Development and application of biodegradable and environment friendly oil proof agents is the trend of oil proof packaging in the future. At the same time, the cost of oil proof packaging could be controlled from the structure of paper, the cost of oil proof agent and the way of adding agent into paper.