The aim of this work was to explore the impact of Optical Brightening Agents on paper printing color management. Two type of Japanese Fuji xerox color papers of 300 g/m2 were chosen, one with Optical Brightening Agents, the other without Optical Brightening Agents, and KONICA MINOLTA C6000 printer was used to output colors, then the color differences between the input and output on the two kinds of paper before and after color management were measured. The color differences under the two conditions above were compared and the impact of Optical Brightening Agents on different tones and ink layer thickness of output colors was analyzed. In addition, the correction of UV-cut filter on Optical Brightening Agents was discussed. The paper containing Optical Brightening Agents output a larger color difference under D50 light source. The influence of fluorescent brighteners on midtone colors was greater than those on bright and dark color tones, while the impact on colors decreased gradually with the decrease of color brightness and the increase of ink film thickness. The impact of the Optical Brightening Agents on the bright color b value was greater than that on the darkened color. The impact of the Optical Brightening Agents on the a value of color was not obvious. The gamut volume of the output color on paper containing Optical Brightening Agents was less than that on paper without Optical Brightening Agents, and the color control ability of paper containing Optical Brightening Agents was greater than paper without Optical Brightening Agents. The difference of output color was reduced after the correction on Optical Brightening Agents with UV-cut, which was significant for copying colors accurately on paper.