Focusing on the existing and possible problems in the storage and transportation process, the application of RFID technology in the assembly packaging in distribution center was explored. Taking the operating mode of the distribution center as an example, combined with the characteristics of IOT technology, the application of RFID technology in packaging, storage and transportation was analyzed by means of flow-diagram. Through analysis of the storage and transportation process in distribution center, the improved operating process after application of the RFID technology was obtained, and the optimized working mode based on RFID was derived. Get and get the optimized. By comparison of the operation flow between the improved system and the previous system, the advantages of using IOT technologies such as RFID were revealed.