The aim of this work was to study the effects of PE/PVA active packaging film containing α-tocopherol on the quality of fresh-cut apple. PE/PVA active packaging films containing different α-tocopherol concentrations were obtained through the solution-coating method and then applied to package fresh-cut apple. The changes of quality indexes were measured periodically during storage, including color, weight loss, firmness, VC content, titratable acid (TA) content and polyphenol oxidase (PPO) activity. The results showed that the PE/PVA active packaging film containing α-tocopherol could slow down browning, weight loss increasing, firmness descending, VC content and titratable acid content reducing of fresh-cut apple and inhibit its PPO activity. The fresh-keeping effectiveness for fresh-cut apple became better with increasing α-tocopherol concentration in PE/PVA active packaging film. In conclusion, it was shown that the PE/PVA active packaging film containing α-tocopherol could slow down the quality change of the fresh-cut apple. It proved that adding antimicrobial or antioxidant agent into packaging film to improve the shelf-life of food was viable.