This paper mainly studied the constitutive model and the vibration of the foam vibration isolation material during transportation. The transport packaging system is a nonlinear complex system with multiple degrees of freedom which involves many factors, such as delivery vehicles, road conditions, internal goods, packaging structure. This article focused on the topic of transport packaging isolation system, based on the typical research in the industry as an example to explore the issue of random excitation of packaged goods in the transport process, dynamic equation of transport packaging system as well as response of vulnerable parts， and on the basis of this exploration, the article proposed some advice on the mechanical performance of transport packaging system. For the transportation, the research on the coupling of the road, vibration isolation material and transport packaging system is not sufficient, and there are still problems to be solved in the field of product protection during transportation. It is of great significance to strengthen researches on the response analysis of coupling system including response analysis of products and test methods for mixed road spectrum for the development of transport packaging.