The aim of this study was to master characteristics of hot-air drying system, and obtain optimal drying technological parameters. Taking drying device of FR400 gravure press as the research subject, the paper researched drying and volatilizing mechanism of solvent in different stages, and established the multi-beam air impacting drying model for suspended hot-air drying device. The paper completed hot-air flow numerical simulation for drying cabinet through fluent, researched hot-air flow state based on structure of drying cabinet, and analyzed generation reasons of turbulence and the influence on drying effect. Air velocity and temperature on surface of presswork were extracted through numerical section technology, fluctuation range and features were analyzed, unevenness in different locations and the causes were discussed, and features of changes in velocity and temperature during the drying process were analyzed. Turbulence was generated on two sides of deflector in the left chamber and the upper right chamber of drying cabinet, and vortex region was formed between tuyeres in interval. The hot-air velocity was more even in the middle but worse at upper and lower sides; the temperature in tuyeres was higher in the middle and at the back, and the drying process was worse in left region. The geometric structure of hot-air drying system has a great influence on drying effect, and the reasonable design on drying cabinet and layout of the graphic area is conducive to drying of printing.