The aim of this study was to investigate the influence of staining of grease on the mechanical properties of corrugated paperboard. Corrugated paperboard was coated with grease. By changing the coating weight and placing time of samples, the influences of stain amount and staining time on the ply adhesive strength, edgewise crush resistance and bursting strength of corrugated paperboard were studied. The ply adhesive strength, edgewise crush resistance and bursting strength gradually decreased with the increase of stain amount, while decreased and then became stable with the increase of staining time. The influence of staining of grease on ply adhesive strength was bigger than those of edgewise crush resistance and bursting strength.