The study aimed to develop a foldable insulation packaging container for aquatic products. A structure design solution of foldable insulation packaging container for aquatic product was obtained based on foldable design idea of paper packaging structure design, using plastic corrugated board and insulation material. Its logistic cost was analyzed compared with the foam box. The mechanical property was measured and analyzed through compression experiment. The results showed that application of this packaging container could significantly reduce the logistics cost when the empty container was in storage and transportation. Its compression strength was better than the common plastic foam box of aquatic product. The global performance could be optimized by adjusting materials of outer box and insulation materials. It was required to add a big plastic bag outside of the aquatic product to satisfy the requirement of avoiding water leakage during logistics when using this packaging container to pack the aquatic product. Taken together, the structure design solution of this foldable insulation packaging container for aquatic product was feasible and sturdy, which provided a basis for the subsequent study on structure optimization, thermal insulation experiment and it application for aquatic products packaging.