This study explored the application of compound fungistat containing oregano essential oil and lemongrass essential oil for the preservation packaging of paper documents. The volatile concentration of fungistat within packaging was analyzed by GC-MS and the change of CFU of mould growing on the surface of paper sample was detected at 35 ℃ , RH90%. With the compound fungistat formula of 0.25 μL/mL lemongrass essential oil mixed with 0.25 μL/mL oregano essential oil, carton coated with the fungistat can delay the mildew cycle of paper inside by 3.7 times, carton packed with fungistat packet can delay it by 4.6 times, compared with the control group. The two kinds of preservation packaging both can control the growth of mould on the paper inside efficiently.