The aim of this work was to establish a GS/MS determination method for glycol ethers and their esters in printing inks used for food packaging. The glycol ethers in inks were enriched by solid-phase microextraction, and the parameters such as extraction mode, extracting fiber, extraction temperature and stirring speed were optimized. The polydimethylsiloxane/divinylbenzene extracting fiber with 65 μm coating showed the highest efficiency. The optimized stirring speed was 250 r/min, extraction temperature was 60 ℃ , extraction time was 15 min, desorption temperature was 275 ℃ , and desorption time was 3 min. All 7 compounds showed good linearity in their mass concentration ranges, with correlation coefficients of above 0.99. The detection limits for the components ranged from 2.5 ng/L to 15.0 ng/L, and the recoveries for spiked samples were between 90.1% and 99.9% with RSDs of 5. 2% to 10.1%. This method had simple and rapid sample pretreatment, and could be used for detection of glycol ethers and their esters in printing inks used for food packaging.