Focusing on the demand of the new model of high speed stick multi-column filling and wrapping machine， it studies a series of interaction interface design. By the analysis of the particularity， comparison and design cases of packaging machine interaction interface，it delivered a interface solution that was a satisfaction for the users in elements of the interface， the consistence of the logic level， the coordination between the tags and page names， over all arrangement， visual styling and transition between the hierarchies. The interface solution proposed accords with the three principles， which are systematic consistent，proper information architecture and humane cognition. By establishing these three principles， it can improve the usability and visual attraction and help to establish a designing standard for the corporation.