To investigate the automatic control methods of thermoforming machines, in order to improve the production efficiency, production quality and the stability of the machine as well as the flexibility of the system. Based on the study of movement control technology of thermoforming machine, the complex logical control relationship in the working process of the thermoforming machine was determined. Some advanced control methods and skills were introduced into the control system of thermoforming machine, such as PLC, location control module, sensor, touch screen etc. The software and hardware systems of the automatic thermoforming machine control system were designed. The control of action sequence, controlling parameters and process parameters was realized. The system operated well, and the function and performance of the thermoforming machine were greatly improved. The system was simple, practical, easy to operate, and had a higher level of control, providing reference for upgrading thermoforming machines.