To establish a method for the determination of Cr, Co, Ni, Cu, As, Se, Cd, Sb, Ba, Hg, Tl and Pb in wooden packing materials by inductively coupled plasma-mass (ICP-MS) with microwave digestion. HNO3+H2O2 were used to com? pletely digest the sample by microwave. 45Sc, 72Ge, 115In and 209Bi were used as internal standard elements to compensate ma? trix effect and signal drift. Octpole collision and reaction cell system (ORS) was used to compensate mass effect. The work? ing parameters of the instrument were optimized. For all elements, the correlation coefficient was between 0.9997 and 1.0000. The detection limits were between 0.01 μg/L and 0.28 μg/L. The recoveries of the method were between 89.4% and 112.5%. The relative standard deviations were between 0.75% and 3.81%. The method was simple, quick and accurate. It was suitable for the determination of the contents of heavy metal elements in wooden packing materials.