To review the research status of some chemical substances in food contact rubber materials and their migration, in order to provide reference for further research. The literatures on the food contact rubber materials and the related health standards in China and other countries in the recent years were summarized. Rubber is widely used in the food industry. Due to the complicated ingredients and manufacturing process of rubber products, the potential chemical migrants are possible to contaminate food, which is harmful to the health of the consumers. As an important part of food safety, enough attention should be paid to the safety problem of the food contact rubber materials. The future research direction should be focused on the detection standards for chemical substances of very high concern and the migration of the non-target chemical substances from food contact rubber materials to food.