Objective To explore intellectualization of the stacker industrial robot and the humanization design method of the operating system. Methods Making full use of the own control system of the industrial robot, data analysis and logical judgment could be done by the industrial robot with the assistance of PLC. A touch screen was used as human-computer interaction interface. Results After debugging, the operating system had features of reasonable interface design, simple operation and monitoring functions, and could accurately control the industrial robot. Conclusion This operating system simplified the operation of industrial robot during sorting or palletizing operations, and improved the adaptability of the robot to objects with different sizes, which is also applicable for other stacker industrial robots.