Objective To investigate the program and hemming process of non-rectangular honeycomb paperboard. Methods Aiming at designated paperboard and its production requirements, the whole process of hemming was classified into work steps on the basis of analyzing the traditional hemming process by the methods of literature search and comparison research. From the classification, angle and stroke data of each step were obtained. Motion working conditions and process route were established and thereby the program was designed. Results Six work steps were classified. Interval feeding of the hemming board was conducted by stepping motor, with a PLC controlling the rotation angle and direction of the motor and paperboard, and a hydraulic system controlling the motion route of the paperboard. Then, the paperboard was hemmed by the hemming machine. Conclusion The program and process could enhance the hemming efficiency of the non-rectangular honeycomb paperboard. It could be widely used for honeycomb paperboard of various shapes and thickness if appropriately improved. Besides, the research will provide reference for automation of the hemming process.