Objective To study the effect of addition of anti-termite agent on adhesives. Methods In this article, we tested the impacts of anti-termite agents bifentrin, deltamentrin and beta-cypermethrin, on the viscosity, pH, curing time, panel surface property and gluing properties of melamine formaldehyde resin. Using the solidification simulation method, we tested the IR absorption spectra of the melamine formaldehyde resin before and after the addition of anti-termite agent. Results The results showed that the pH of melamine-formaldehyde resin was reduced while the viscosity and curing time of melamine-formaldehyde resin were increased and the panel surface property was improved by the addition of anti-termite agent. However ,the bond strength of melamine-formaldehyde resin was declined. Infrared spectrum analysis showed that the characteristic peak of melamine-formaldehyde resin was not influenced by the addition of anti-termite agents. Conclusion Bifentrin, deltamentrin and beta-cypermethrin affected the general characteristics of melamine-formaldehyde resin. There was an adverse effect on shear bong strength of melamine-formaldehyde resin due to the moisture and original drug fine particles. The chemical groups of melamine formaldehyde resin were not influenced by bifentrin, deltamentrin and beta-cypermethrin.