Objective To provide protection for products with rigid antioxidant requirements and a more reliable antioxidant packing process. Methods This paper designed a new antioxidant packing process-the oxygen-free packing process, through the study of the common antioxidant packing processes in present, and analysis on the principle and effects of the commonly used deoxidization technologies in space. Results This paper put forward the related concepts of oxygen-free packing for the first time, divided the deoxidizing levels of oxygen-free packing, designed the process flowchart and implementation of oxygenfree packing. The oxygen-free packing process included two sections: confined space system and deoxidizing system. This paper designed the structure of the confined space and the process principle of the deoxidizing system. Conclusion Employment of the oxygen-free packing process could overcome the problems in traditional antioxidant packing, which was suitable for more rigidly antioxidant protection. The oxygen-free packing process brought the remaining oxygen to lower than 0. 0001% and the remaining oxygen could be controlled therein.