Objective To study the termite-resisting function of packing wood-based panel. Methods Mothproof plywood was manufactured using poplar veneer and melamine formaldehyde resin( MF) which were previously mixed with erther bifentrin, deltamentrin, or beta-cypermethrin. In this article, we tested the viscosity of melamine formaldehyde resin and the mechanical properties of mothproof plywood. This study evaluated the ability of termites to decompose pest control-treated or untreated plywood by termite mortality rate. Results The results suggested that the anti-termite agent was uniformly dispersed in the MF resin, and was not stratified. The bonding strength was declined. Deltamentrin and beta-cypermethrin had adverse effects on MOE and MOR, but its concentration had no significant effect on MOE and MOR. Conclusion When the ratio of bifenthrin and MF was 1. 25% , or ratio of deltamethrin and MF was 5% , or ratio of efficient deltamethrin and MF was 2. 2% ,the plywood had the best anti-termite performance, the termite mortality rate reached 100% , and the main mechanical properties met the national standard.