Objective To develop a GC-MS method for the simultaneous determination of TEC, TBC, ATBC, and TOC in food packaging materials. Methods N-hexane ultrasonic extraction was used to process samples, the targets were qualitatively characterized by full scan, and ion scanning was selected for quantification. Results All the correlation coefficients ( r) of the 4 kinds of plasticizer were above 0. 997, the recoveries were 92. 7% ~ 102. 3% , and the relative standard deviations ( RSD) of the method were 3. 2% ~ 7. 3% . Conclusion The method is rapid, sensitive, highly precise and reproducible, and is suitable for monitoring the four citrate plasticizers in food packages.