Objective To reduce the production cost of paper plastic composite corrugated cardboard. Methods Through the study of the corrugated tooth profile parameters, a mathematical model was established using corrugating coefficient as the target function, which was then optimized using the genetic algorithm toolbox in MATLAB platform, and the optimized results were compared with the existing corrugated roller parameters. Results After optimization, the top radius, fillet radius and flute height of the corrugated roller teeth were reduced, the flute number was increased, the corrugating coefficient was decreased,the paper consumption was reduced and the production cost was decreased. Conclusion By optimizing the tooth profile parameter model of the corrugating coefficient using the genetic algorithm toolbox in MATLAB platform, the top radius and fillet radius of the corrugated roller teeth were reduced by 0. 161 mm, 0. 111 mm, the flute number was increased by 1. 268, the flute height was decreased by 0. 955 mm, and the corrugating coefficient was decreased by 0. 1801. The decrease in the corrugating coefficient indicated the decrease in paper consumption, which can significantly reduce the cost of production.