Objective To study the preservation mechanism, the current research status and future research directions of ultra high pressure fresh-keeping packaging technology. Methods Ultra high pressure processing ( UHPP) is a new type of non thermal processing technology used to achieve the purpose of sterilization mainly through destruction of the cell wall structure, cell membrane and intercellular space of the microorganisms, denaturation of proteins, as well as decreasing the enzyme activity. This article illustrated the application and development of ultra high pressure sterilization technology in aquatic product industry, meat industry and the vegetable and fruit products industry and other aspects. Conclusion Ultra high pressure fresh keeping packaging technology is still in its infancy, the present study also focused on the aspect of technique, so far there is relatively little research on the mechanism of preservation. With the development of researching on ultra high pressure fresh keeping packaging technology, there will be more and more deep study on the related mechanism.