Objective To research the accurate and efficient evaluation methods of the digital proofing color reproduction quality at digital workflow. Methods The 1617 color piece of the IT8. 7 / 4 color table was divided and intrinsic relations between the color difference of each partition, dot enlargement, L value replication curve and the digital proof color quality were analyzed. The key points which affect the digital sample color quality were counted. Results The experiment showed that the average color difference of each partition were around 0. 5, with a maximum color difference of less than 3, and the L replication curve was smooth, which meant that the color reproduction quality was good. However, the yellow dot color difference was big, the replication curve was not smooth, and gradual richness reappearance was bad. Therefore, the parameters related to yellow should be adjusted to improve the color reproduction quality. Conclusion The relationship between color difference, dot enlargement, L value replication curve and the digital sample quality proves the feasibility and precision of the color quality evaluation scheme.