The cross-linked carboxymethyl corn starch (CCMS) / wheat gluten(WG) packaging films were prepared by solution mixing technique. The effects of the wheat gluten amount, CCMS amount and glycerin amount on the comprehensive performance evaluation of value of CCMS/ WG Composite packaging film were studied according to response surface methodology analysis and the regression equation were established. The optimum technology conditions were confirmed as follow:the film thickness 0. 096 mm, tensile strength was 20. 3 MPa, tensile elongation at break was 39. 1%,puncture strength was 5. 73 J/ mm, water vapor permeability was 3. 58 g·mm/ (m2 ·d·kPa),oxygen permeability was 0. 69×10-15 cm3 ·cm/ (m2 ·s·Pa) and light transmittance of CCMS/ WG composite packaging film was 37. 6% when the additive amount of wheat gluten was 0. 65 g, the additive amount of CCMS was 4. 77 g and the additive amount of glycerin was 1. 05 g. The Comprehensive performance evaluation of value of CCMS/ WG Composite packaging film was up to 15. 73.