A method was established for determining bisphenol A (BPA) in coatings of metal food cans by high performance liquid chromatography with fluorescence detection. Samples were ultrasonic extracted with methanol. The peak area and concentration of BPA has a better linear relationship in the range of 0. 1 μg/ mL to 20. 0 μg/ mL ( r = 0. 9985). The linear equation is y=19. 241x+2. 7916. The limit of detection is 0. 05 μg/ mL. Recovery of the method is 95. 0% ~100. 9% . The BPA contents of several batches coating from different suppliers were compared. It was concluded that the method is sensitive, reliable, accurate and fit for BPA quantitative determination in metal food cans.