Polypropylene resin was melt blending with nano-silica to reduce the adsorption, solubility, and diffusivity of polypropylene against organic solvent by means of changing crystallinity, glass transition temperature, and solubility parameter of polypropylene. As a result, the solvent residue value of polypropylene film after printing was reduced. The experiments showed that nano-silica can significantly improve crystallinity and glass transition temperature of polypropylene, and reduce the proportion of amorphous region; the modified polypropylene shows a low residual value against not only non-polar solvent but also common polar solvent.