Wood honeycomb sandwich board is a green material with good performance, which is mainly used in furniture and packaging industry. The performance of the honeycomb sandwich board with different wood structure was studied according to the principle of sandwich construction. The results showed that the lateral pressure strength of the board is mainly decided by the faceplate strength; the effect of different faceplate on flat compressive strength is not significant; when the plywood is used as the faceplate, the bending resistance is the best and the bending strength reaches 7. 720 MPa and the bending modulus reaches 1582 MPa.