The relationship among material parameters of orthotropic paper was studied to reduce the independent parameters of paper performance for reasonable parameter matching in paper structure. The deformations of material unit in pure shear loading and pure normal stress loading were compared. The relationship among elastic modulus, shear modulus and Poisson's ratio was obtained and a simple mathematic equation of the relationship was educed. The purpose was to provide reference structure design, deformation calculation, vibration analysis and FEM simulation of orthotropic paper.