The formula of UV offset ink was designed and 4 different fillers were chosen to make the ink respectively. The ink performance such as viscosity, curing time, fineness and scuff resistance were tested. The results showed that different fillers and different percentage of fillers has different influence on ink performance; scuff resistance can be enhanced obviously by adding barium sulfate; when using titanium dioxide as filler of the ink and the quantity of filler is 5%, small fineness, modest viscosity and short curing time as well as high scuff resistance of ink can be obtained.